OPTIMIZATION OF SEPARATION OF THE PHASES OF PETASITIDIS RADIX EXTRACT SUBJECTED TO PRE-PROCESSING WITH GLYCERIN AND LACTIC ACID

LATIFI, Mahi and LATIFI, Ejup and JASHARI, Nazif and KUCHI, Jeton (2022) OPTIMIZATION OF SEPARATION OF THE PHASES OF PETASITIDIS RADIX EXTRACT SUBJECTED TO PRE-PROCESSING WITH GLYCERIN AND LACTIC ACID. Journal of Natural Sciences and Mathematics of UT, 7 (13-14). pp. 284-287. ISSN 2671-3039

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Abstract

The obtained extract from the roots of Petasitidis Radix belongs to the group of extremely complicated extracts due to appearance of a two-phase or three-phase solvent during the process of separation after the extraction process and the concentration, where is present pyrrolizidine which is a part of the group of toxic and poisonous materials. This is the reason why obtained extract, up to the phase separation, has an amount lower than 0.1 % in its content a phase of Pyrrolizidine, in order to remove the remaining amount of pyrrolizidine, by absorption. This is reached by using a different chemical adsorbent –of Lewatit, or bio-absorbent – diatomaceous earth, pharmaceutical Zeolite, etc. This dividing is done with separation of the phases, but not always is reached a complete separation, therefore a large amount is removed and is thrown in order to have a clear extract. In this paper work it was performed a pre-processing with Glycerin and lactic acid, a method which gives very good results and the extract losses are at minimum.

Item Type:	Article
Uncontrolled Keywords:	extract, pyrrolizidine, glycerin, lactic acid
Subjects:	Q Science > QD Chemistry
Divisions:	Faculty of Engineering, Science and Mathematics > School of Chemistry
Depositing User:	Unnamed user with email zshi@unite.edu.mk
Date Deposited:	31 Oct 2022 15:15
Last Modified:	31 Oct 2022 15:15
URI:	http://eprints.unite.edu.mk/id/eprint/1089

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