ISAKI, Rezearta and KAMBERI, Maida and SELMANI, Driton (2026) PREVALENCE OF ANTIBIOTIC RESISTANCE IN CLINICAL ISOLATES OF E. COLI. In: INTERNATIONAL CONFERENCE “FROM RESEARCH TO APPLICATION”, 20 May, 2026.
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Abstract
Antimicrobial resistance (AMR) represents one of the most pressing global public health challenges of the 21st century. Among Gram-negative pathogens, Escherichia coli (E. coli) plays a central role due to its dual nature as a commensal organism and a frequent opportunistic pathogen. This review critically evaluates the prevalence, molecular mechanisms, and epidemiological distribution of antibiotic resistance in clinical isolates of E. coli. Evidence from multiple peer-reviewed studies demonstrates a significant rise in multidrug-resistant (MDR) and extended-spectrum beta-lactamase (ESBL)-producing strains, particularly in hospital environments. Resistance to first-line antibiotics such as ampicillin, fluoroquinolones, and third-generation cephalosporins is highly prevalent, while reduced susceptibility to carbapenems has emerged as an alarming trend. The findings emphasize the urgent necessity for antimicrobial stewardship programs, strengthened surveillance systems, and global coordinated interventions.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Faculty of Law, Arts and Social Sciences > School of Social Sciences |
| Depositing User: | Unnamed user with email zshi@unite.edu.mk |
| Date Deposited: | 10 Sep 2026 12:37 |
| Last Modified: | 10 Sep 2026 12:37 |
| URI: | http://eprints.unite.edu.mk/id/eprint/2393 |
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