INSTRUMENTAL PHARMACEUTICAL ANALYSIS OF VITAMIN B12 IN PHARMACEUTICAL PRODUCTS AND DIETARY SUPPLEMENTS: A REVIEW

ALIJA, Gjylai and Bexheti, Dorentina and DAUTI, Merita and Y.-Havziu, Drita and Nuhii, Nexhibe and IBRAIMI, Qail and A.-LIKA, Sihana and A.-IDRIZI, Edita and H.-ZAJMI, Arlinda and BALLAZHI, Lulzime and SHABANI, Arijeta and IDRIZI, Taulant (2026) INSTRUMENTAL PHARMACEUTICAL ANALYSIS OF VITAMIN B12 IN PHARMACEUTICAL PRODUCTS AND DIETARY SUPPLEMENTS: A REVIEW. In: INTERNATIONAL CONFERENCE “FROM RESEARCH TO APPLICATION”, 20 May, 2026.

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Abstract

Vitamin B12, or cobalamin, is a water-soluble vitamin that is vital for the proper functioning of the human body. It plays important roles in the formation of red blood cells, DNA synthesis, and the functioning of the nervous system. A deficiency in this vitamin can result in megaloblastic anemia, fatigue, weakness, neurological issues, and memory problems. Consequently, Vitamin B12 supplements are commonly utilized, particularly among older adults, vegetarians, vegans, and individuals with gastrointestinal absorption disorders. The growing use of dietary supplements has made the analysis of Vitamin B12 essential in pharmaceutical and food quality control. The primary goal of this analysis is to assess the actual quantity of vitamin present in the product and confirm whether it aligns with the value stated on the label. LC-MS/MS is an advanced analytical technique used for determining Vitamin B12 in dietary supplements and pharmaceutical preparations. Furthermore, the analysis is used to examine the stability of the vitamin during storage, detect potential degradation, and ensure the safety and effectiveness of the supplement.

Item Type: Conference or Workshop Item (Paper)
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: Unnamed user with email zshi@unite.edu.mk
Date Deposited: 24 Sep 2026 09:18
Last Modified: 24 Sep 2026 09:18
URI: http://eprints.unite.edu.mk/id/eprint/2481

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