CLINICAL MANIFESTATIONS OF HERPES ZOSTER OPHTHALMICUS

ADEMI, Lejla and ADEMI JONUZI, Emira (2026) CLINICAL MANIFESTATIONS OF HERPES ZOSTER OPHTHALMICUS. In: INTERNATIONAL CONFERENCE “FROM RESEARCH TO APPLICATION”, 20 May, 2026.

[img] Text
Proceedings Book 2026-2 (1)-955-962.pdf
Download (645kB)

Abstract

Background: Herpes zoster ophthalmicus (HZO), which accounts for 10–20% of herpes zoster (HZ) cases, involves the first division of the trigeminal nerve.It is considered a medical emergency due to its potential to significantly affect visual function and quality of life. The aim of this study was to evaluate the clinical manifestations of hospitalized patient with HZO and to identify potential factors associated with the time to improvement of skin rash and the duration of ocular symptoms at discharge. Material and methods:Our case report is a 33-year-old man who presented with left-sided orbital and temporal stabbing pain, accompanied by swelling in the left frontal region that later extended to the left ocular area, with upper eyelid edema, burning, and tearing. Due to the persistence of swelling and pain, the patient was referred to the Department of Infectious Diseases, hospitalized for further evaluation and treatment. Results and Conclusion: Varicella-zoster virus–specific cell-mediated immunity, which maintains latent VZV under control and is reinforced by periodic re-exposure, represents a key mechanism in preventing viral reactivation and the development of HZ. Clinical manifestations include dermatomal vesicular rash, acute ocular pain, and prodromal symptoms. Slit-lamp biomicroscopy is necessary to identify ocular complications, while corneal sensation testing is recommended to detect neurotrophic keratopathy. Initial treatment consists of systemic antivirals, including acyclovir, with assessment for possible immunocompromise. Advanced age is not the sole risk factor for HZO, as the disease may occur at any age. This case indicates that stress and other factors may contribute to VZV reactivation in middle-aged patients.. Whereas older age appears to be mainly associated with delayed healing of skin lesions.

Item Type: Conference or Workshop Item (Paper)
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email zshi@unite.edu.mk
Date Deposited: 24 Sep 2026 09:30
Last Modified: 24 Sep 2026 09:30
URI: http://eprints.unite.edu.mk/id/eprint/2483

Actions (login required)

View Item View Item
Universiteti i Tetoves is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.