HORMONAL IMBALANCES AS DETERMINANT OF INFETILITY

LATIFI, Medina and ABDULI, Mergime and F. MEMISHI, Sheval (2026) HORMONAL IMBALANCES AS DETERMINANT OF INFETILITY. JNSM Journal of Natural Sciences and Mathematics of UT, 11 (21-22). pp. 93-98.

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Abstract

Infertility represents a major reproductive health concern affecting both women and men worldwide, with hormonal imbalances being among the most significant underlying determinants. The endocrine system plays a crucial role in regulating ovulation, spermatogenesis, implantation, and overall reproductive function through hormones such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), estrogen, progesterone, testosterone, prolactin, and thyroid hormones. Disruptions in these hormonal pathways may lead to anovulation, menstrual irregularities, impaired follicular development, reduced sperm quality, and altered endometrial receptivity. Common clinical conditions associated with hormonal infertility include polycystic ovary syndrome (PCOS), thyroid dysfunction, hyperprolactinemia, hypogonadism, and insulin resistance. This paper aims to analyze the relationship between hormonal dysregulation and infertility by examining the main hormonal factors involved, their physiological impact on reproductive processes, and the diagnostic approaches used in clinical practice. Furthermore, it highlights evidence-based strategies for management, including lifestyle modifications, pharmacological interventions, and assisted reproductive technologies. A deeper understanding of hormonal imbalances and their reproductive consequences is essential for early diagnosis, personalized treatment, and improved fertility outcomes.

Item Type: Article
Subjects: Q Science > Q Science (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User: Unnamed user with email zshi@unite.edu.mk
Date Deposited: 26 Oct 2026 12:22
Last Modified: 26 Oct 2026 12:22
URI: http://eprints.unite.edu.mk/id/eprint/2668

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