EXCIPIENTS IN COSMETIC SCIENCE: BALANCING FUNCTIONALITY AND TOXICOLOGICAL SAFETY - A CRITICAL REVIEW OF EMERGING FORMULATION STRATEGIES

DAUTI, Merita and AHMETI- LIKA, Sihana and Yzeiri HAVZIU, Drita and ALIJA, Gjylai and ALILI-IDRIZI, Edita and BALLAZHI, Lulzime and HAXHIU-ZAJMI, Arlinda and IBRAIMI, Qahil (2025) EXCIPIENTS IN COSMETIC SCIENCE: BALANCING FUNCTIONALITY AND TOXICOLOGICAL SAFETY - A CRITICAL REVIEW OF EMERGING FORMULATION STRATEGIES. International Journal of Medical Sciences, 10 (19-20). pp. 230-240. ISSN 2545 - 4870

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Abstract

The rapid expansion of the cosmetic industry and the increasing availability of personal care products have raised growing concerns regarding the toxicological safety of ingredients commonly used in cosmetic formulations. Aim: This review aims to provide a comprehensive evaluation of the toxic potential of selected cosmetic ingredients and their associated health risks, focusing on systemic toxicity, endocrine disruption, developmental interference, respiratory implications, and carcinogenicity. Methods: The analysis synthesizes recent toxicological studies, encompassing both short-term and long-term assessments, alongside a review of international regulatory frameworks governing cosmetic ingredient safety. Results: Evidence indicates that several substances continue to be widely used in cosmetic formulations despite increasing data highlighting their potential adverse health effects. These include risks related to systemic toxicity, endocrine disruption, developmental effects, respiratory issues, and carcinogenicity. Conclusion: The findings underscore the urgent need for enhanced scientific scrutiny, stricter regulatory policies, and a harmonized global approach to cosmetic safety. Ongoing research and reformulation strategies are critical to the development of safer cosmetic products and the advancement of more rigorous, transparent safety standards within the industry.

Item Type:	Article
Uncontrolled Keywords:	Cosmetic ingredients, systemic toxicity, health risks, cosmetic formulations, regulatory oversight, Safety standards, toxicological studies, product reformulation
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User:	Unnamed user with email zshi@unite.edu.mk
Date Deposited:	26 Dec 2025 00:04
Last Modified:	26 Dec 2025 00:04
URI:	http://eprints.unite.edu.mk/id/eprint/2285

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