IMPACT OF VITAMIN D DEFICIENCY ON HEMATOLOGICAL PARAMETERS

SHABANI, Luzana and ALI, Jehona and BEADINI, Sheqibe and BAFQARI-BAKIJI, Mimoza and SABRIU HAXHIJAHA, Arita (2026) IMPACT OF VITAMIN D DEFICIENCY ON HEMATOLOGICAL PARAMETERS. In: 2026 International Congress "From Research to Application", 20 May 2026, University of Tetova, Tetova, North Macedonia.

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Abstract

Vitamin D is a steroid hormone with an important role in bone metabolism and immune function, while its deficiency represents a global health problem. This study aims to evaluate the relationship between vitamin D levels and hematological parameters, including the neutrophil-to-lymphocyte ratio (N/L), as an indicator of inflammation. This retrospective study included 201 outpatient individuals of different ages, analyzed during the period September 2025 – March 2026 at the Clinical Hospital of Tetovo. Patients were divided into three groups according to vitamin D levels: >30 ng/ml, 20–30 ng/ml, and <20 ng/ml. The results showed that 47.8% of patients had vitamin D deficiency. Analysis of hematological parameters indicated no statistically significant differences in erythrocyte and leukocyte counts among the groups. However, for hemoglobin, a statistically significant difference was observed between the group with levels of 20–30 ng/ml and the group with <20 ng/ml (p=0.017), suggesting a possible association between vitamin D deficiency and decreased hemoglobin levels. Additionally, the N/L ratio was significantly higher in patients with vitamin D deficiency, with statistically significant differences between groups (<20 ng/ml compared to the other groups), indicating a potential link with inflammatory processes. In conclusion, vitamin D deficiency is associated with partial changes in hematological parameters, particularly with decreased hemoglobin and increased N/L ratio. These findings suggest a potential role of vitamin D in modulating inflammation and hematological status, highlighting the importance of its monitoring in clinical practice.

Item Type: Conference or Workshop Item (Paper)
Subjects: Q Science > Q Science (General)
Divisions: Faculty of Engineering, Science and Mathematics > School of Mathematics
Depositing User: Unnamed user with email zshi@unite.edu.mk
Date Deposited: 01 Jul 2026 09:43
Last Modified: 01 Jul 2026 09:43
URI: http://eprints.unite.edu.mk/id/eprint/2358

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